RCC1 and PKM

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RCC1	PKM
Description		regulator of chromosome condensation 1	pyruvate kinase M1/2
Image
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex	Extracellular Region Nucleus Cytoplasm Mitochondrion Cytosol Cilium Vesicle Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Pyruvate Kinase Complex Extracellular Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Ran GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity	Magnesium Ion Binding RNA Binding Pyruvate Kinase Activity Protein Binding ATP Binding Kinase Activity MHC Class II Protein Complex Binding Potassium Ion Binding Identical Protein Binding ADP Binding Cadherin Binding Thyroid Hormone Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly	Response To Hypoxia Liver Development Glycolytic Process ATP Biosynthetic Process Response To Nutrient Response To Gravity Programmed Cell Death Response To Muscle Inactivity Animal Organ Regeneration Cellular Response To Insulin Stimulus Pyruvate Biosynthetic Process Neutrophil Degranulation Skeletal Muscle Tissue Regeneration Canonical Glycolysis Positive Regulation Of Sprouting Angiogenesis
Pathways		Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation	Neutrophil degranulation
Drugs			Pyruvic acid L-Phospholactate 2-Phosphoglycolic Acid 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine Copper Artenimol
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		49 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	46 interacting genes: ANXA7 APP ARAF AURKB CDC25A CDK4 CDKN1A CTNNB1 EGLN3 EPM2A EXOSC5 GRB7 HERC1 HIF1A KPNA1 LMO7 LNX1 MAPK1 MDM2 MYL2 MYOC NAGK NDRG1 NXT2 OLFM2 PAX8 PIN1 POLE2 PRKN PTEN RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 SUMO1 TERF1 TINF2 TK1 TRIM35 TRIM63 UCHL5 YWHAQ
Entrez ID		1104	5315
HPRD ID		01559	01529
Ensembl ID		ENSG00000180198	ENSG00000067225
Uniprot IDs		A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081	A0A024R5Z9 B4DNK4 P14618 V9HWB8
PDB IDs		1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB	1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG 4QG6 4QG8 4QG9 4QGC 4RPP 4WJ8 4YJ5 5X0I 5X1V 5X1W 6B6U 6GG3 6GG4 6GG5 6GG6 6NU1 6NU5 6NUB
Enriched GO Terms of Interacting Partners?
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