TRIM23 and ATXN7

Number of citations of the paper that reports this interaction (PubMedID 21078624)
23

Data Source:
BioGRID (two hybrid)

		TRIM23	ATXN7
Description		tripartite motif containing 23	ataxin 7
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Lysosomal Membrane Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytosol Microtubule Cytoskeleton Nuclear Matrix
	Molecular Function	Nucleic Acid Binding GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding GDP Binding Identical Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Viral Process Vesicle-mediated Transport Protein Ubiquitination Positive Regulation Of Catalytic Activity Innate Immune Response	Microtubule Cytoskeleton Organization Nucleus Organization Negative Regulation Of Microtubule Depolymerization Visual Perception Histone Deubiquitination Protein Deubiquitination
Pathways			HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 31152163) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458)
Interacting Genes		151 interacting genes: - ACTN4 AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GLIDR GMCL2 GPANK1 GPKOW HAUS1 HNRNPLL HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RAMAC RIBC2 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TASOR2 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581 ZNF688	60 interacting genes: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN IMPDH2 ITPRID2 JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 USP22 VCP VWF
Entrez ID		373	6314
HPRD ID		03449	06365
Ensembl ID		ENSG00000113595	ENSG00000163635
Uniprot IDs		P36406	O15265 Q9UPD8
PDB IDs		5VZV 5VZW	2KKR
Enriched GO Terms of Interacting Partners?
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