ITGB4 and CLCA2

Number of citations of the paper that reports this interaction (PubMedID 12110680)
39

Data Source:
HPRD (in vivo, in vitro)

		ITGB4	CLCA2
Description		integrin subunit beta 4	chloride channel accessory 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Cell Junction Hemidesmosome Cell Leading Edge Nuclear Membrane Receptor Complex Extracellular Exosome	Extracellular Region Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Junction Nuclear Membrane
	Molecular Function	G Protein-coupled Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Metallopeptidase Activity Ligand-gated Ion Channel Activity Metal Ion Binding
	Biological Process	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Cell Adhesion Mediated By Integrin Nail Development Skin Morphogenesis Mesodermal Cell Differentiation Cell Motility	Proteolysis Cell Adhesion Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Assembly of collagen fibrils and other multimeric structures Laminin interactions Syndecan interactions Type I hemidesmosome assembly	Stimuli-sensing channels
Drugs		R1295
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS			Crohn's disease-related phenotypes ( 25557950)
Interacting Genes		25 interacting genes: ALOX12 ATXN1 CLCA1 CLCA2 COL17A1 DST EIF6 ERBB2 ERBIN FYN GRB2 ITGA6 MET PLEC PRKCA PRKCD PTK2 SDC2 SDC3 SHC1 SREBF2 VIM YES1 YWHAB YWHAQ	1 interacting genes: ITGB4
Entrez ID		3691	9635
HPRD ID		00946	04923
Ensembl ID		ENSG00000132470	ENSG00000137975
Uniprot IDs		A0A024R8K7 A0A024R8N2 A0A024R8T0 B7ZLD8 P16144	Q9UQC9
PDB IDs		1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A 4Q58 4WTW 4WTX 6GVK 6GVL
Enriched GO Terms of Interacting Partners?
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