ITGB4 and COL17A1

Number of citations of the paper that reports this interaction (PubMedID 9660880)
48

Data Source:
HPRD (in vivo, two hybrid)

		ITGB4	COL17A1
Description		integrin subunit beta 4	collagen type XVII alpha 1 chain
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Cell Junction Hemidesmosome Cell Leading Edge Nuclear Membrane Receptor Complex Extracellular Exosome	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	G Protein-coupled Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Cell Adhesion Mediated By Integrin Nail Development Skin Morphogenesis Mesodermal Cell Differentiation Cell Motility	Cell-matrix Adhesion Epidermis Development Extracellular Matrix Organization Hemidesmosome Assembly Regulation Of Immune Response
Pathways		Assembly of collagen fibrils and other multimeric structures Laminin interactions Syndecan interactions Type I hemidesmosome assembly	Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization
Drugs		R1295
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)	Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS			Cardiac hypertrophy ( 21348951)
Interacting Genes		25 interacting genes: ALOX12 ATXN1 CLCA1 CLCA2 COL17A1 DST EIF6 ERBB2 ERBIN FYN GRB2 ITGA6 MET PLEC PRKCA PRKCD PTK2 SDC2 SDC3 SHC1 SREBF2 VIM YES1 YWHAB YWHAQ	12 interacting genes: ACTN1 ACTN4 CLSTN1 CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PPL
Entrez ID		3691	1308
HPRD ID		00946	00223
Ensembl ID		ENSG00000132470	ENSG00000065618
Uniprot IDs		A0A024R8K7 A0A024R8N2 A0A024R8T0 B7ZLD8 P16144	Q9UMD9
PDB IDs		1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A 4Q58 4WTW 4WTX 6GVK 6GVL
Enriched GO Terms of Interacting Partners?
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