IRS1 and UBTF

  • Number of citations of the paper that reports this interaction (PubMedID 12554758)
  • 26
  • Data Source:
  • HPRD (in vivo)

IRS1

UBTF

Description insulin receptor substrate 1 upstream binding transcription factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Diverticular disease ( 30177863)
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes 78 interacting genes: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK3 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 NUMB PASK PDPK1 PELI1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRD PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBC UBTF YWHAB YWHAE YWHAG YWHAZ 33 interacting genes: AURKA CCNA2 CCND1 CCNE1 CD3EAP CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 EP300 IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2
Entrez ID 3667 7343
HPRD ID 00943 02814
Ensembl ID ENSG00000169047 ENSG00000108312
Uniprot IDs P35568 P17480
PDB IDs 1IRS 1K3A 1QQG 2Z8C 5U1M 6BNT 1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?
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