HUS1 and FEN1

  • Number of citations of the paper that reports this interaction (PubMedID 19535328)
  • 36
  • Data Source:
  • BioGRID (pull down, pull down, affinity chromatography technology, affinity chromatography technology)

HUS1

FEN1

Description HUS1 checkpoint clamp component flap structure-specific endonuclease 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507)
  • Asthma ( 31619474)
  • Bipolar disorder ( 28115744 31043756)
  • Bipolar I disorder ( 31043756)
  • Colorectal cancer ( 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Crohn's disease ( 28067908)
  • Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483 23378610)
  • Oleic acid (18:1n-9) levels ( 23362303)
  • Palmitoleic acid (16:1n-7) levels ( 23362303)
  • Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
  • Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
  • Platelet count ( 22139419)
  • Red blood cell fatty acid levels ( 25500335)
  • Resting heart rate ( 27798624)
  • Serum metabolite levels ( 23093944)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Stearic acid (18:0) levels ( 23362303)
Interacting Genes 23 interacting genes: CD200 DNAJC7 FEN1 HDAC1 HUS1B MSH2 MSH3 MSH6 NEIL1 OGG1 PCNA POLB RAD1 RAD17 RAD9A RAD9B RHNO1 RPA1 RPA2 SIRT6 TDG TOPBP1 YWHAQ 18 interacting genes: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 HUS1 PCNA RAD1 RAD9A TERF1 WDR4 WRN
Entrez ID 3364 2237
HPRD ID 04787 02670
Ensembl ID ENSG00000136273 ENSG00000168496
Uniprot IDs A4D2F2 O60921 P39748 Q6FHX6
PDB IDs 3A1J 3G65 3GGR 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU 5E0V 5FV7 5K97 5KSE 5UM9 5ZOD 5ZOE 5ZOF 5ZOG
Enriched GO Terms of Interacting Partners?
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