HUS1 and HUS1B

Number of citations of the paper that reports this interaction (PubMedID 11944979)
9

Data Source:
HPRD (in vivo)

		HUS1	HUS1B
Description		HUS1 checkpoint clamp component	HUS1 checkpoint clamp component B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Checkpoint Clamp Complex Site Of Double-strand Break	Nucleolus Checkpoint Clamp Complex Site Of Double-strand Break
	Molecular Function	Protein Binding
	Biological Process	DNA Damage Checkpoint Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Nucleotide-excision Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Negative Regulation Of DNA Replication Response To UV Embryo Development Ending In Birth Or Egg Hatching Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Nucleotide-excision Repair Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507)	Aging ( 22773346) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: CD200 DNAJC7 FEN1 HDAC1 HUS1B MSH2 MSH3 MSH6 NEIL1 OGG1 PCNA POLB RAD1 RAD17 RAD9A RAD9B RHNO1 RPA1 RPA2 SIRT6 TDG TOPBP1 YWHAQ	4 interacting genes: HUS1 RAD1 RAD9A RAD9B
Entrez ID		3364	135458
HPRD ID		04787	13722
Ensembl ID		ENSG00000136273	ENSG00000188996
Uniprot IDs		A4D2F2 O60921	Q8NHY5
PDB IDs		3A1J 3G65 3GGR
Enriched GO Terms of Interacting Partners?
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