HOXA1 and ADAMTSL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOXA1	ADAMTSL4
Description		homeobox A1	ADAMTS like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Interstitial Matrix Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding	Protease Binding Protein Binding Peptidase Activity
	Biological Process	Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis	Epithelial Cell Development Proteolysis Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases		Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome	Ectopia lentis
GWAS		Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)	Coronary artery disease ( 29212778) Migraine ( 27322543) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		62 interacting genes: ADAMTSL4 ALG13 BLZF1 CCDC33 CHIC2 CHRD DUSP22 EFEMP2 GATA1 GP9 GRN KDM1A KRT31 KRT38 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NLA PBX2 PIK3R1 PKNOX1 PLSCR1 PRMT6 RBCK1 RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAF2 TRAPPC6A TRIM42 TRIP6	110 interacting genes: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 CATSPER1 CCDC26 CFAP206 CHCHD2 CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL2 GNE GNMT GOLGA8EP HGF HNRNPLL HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LHX4 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 OTX1 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SHFL SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		3198	54507
HPRD ID		00843	18237
Ensembl ID		ENSG00000105991	ENSG00000143382
Uniprot IDs		P49639	B7ZMJ3 Q6UY14 Q9UFG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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