HOXA1 and TBC1D10C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOXA1	TBC1D10C
Description		homeobox A1	TBC1 domain family member 10C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Cytosol Plasma Membrane Membrane Filopodium Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis	Intracellular Protein Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Negative Regulation Of B Cell Activation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Calcineurin-NFAT Signaling Cascade Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Neutrophil degranulation TBC/RABGAPs
Drugs
Diseases		Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		62 interacting genes: ADAMTSL4 ALG13 BLZF1 CCDC33 CHIC2 CHRD DUSP22 EFEMP2 GATA1 GP9 GRN KDM1A KRT31 KRT38 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NLA PBX2 PIK3R1 PKNOX1 PLSCR1 PRMT6 RBCK1 RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAF2 TRAPPC6A TRIM42 TRIP6	7 interacting genes: APP HOXA1 KLHL12 KRTAP13-1 KRTAP5-9 NOTCH2NLA PPP3R2
Entrez ID		3198	374403
HPRD ID		00843	13330
Ensembl ID		ENSG00000105991	ENSG00000175463
Uniprot IDs		P49639	Q8IV04
PDB IDs
Enriched GO Terms of Interacting Partners?
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