ADAMTSL4 and RHOJ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	RHOJ
Description		ADAMTS like 4	ras homolog family member J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Interstitial Matrix Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Peptidase Activity	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Epithelial Cell Development Proteolysis Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process	Angiogenesis Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Rho GTPase cycle
Drugs
Diseases		Ectopia lentis
GWAS		Coronary artery disease ( 29212778) Migraine ( 27322543) Rhegmatogenous retinal detachment ( 23585552)	Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)
Interacting Genes		110 interacting genes: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 CATSPER1 CCDC26 CFAP206 CHCHD2 CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL2 GNE GNMT GOLGA8EP HGF HNRNPLL HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LHX4 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 OTX1 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SHFL SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	20 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 CDC42EP1 DOCK10 DOCK8 MEOX2 PAK1 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS WASL
Entrez ID		54507	57381
HPRD ID		18237	09632
Ensembl ID		ENSG00000143382	ENSG00000126785
Uniprot IDs		B7ZMJ3 Q6UY14 Q9UFG7	A0A024R692 Q7Z513 Q9H4E5
PDB IDs
Enriched GO Terms of Interacting Partners?
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