ADAMTSL4 and ZNF587

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	ZNF587
Description		ADAMTS like 4	zinc finger protein 587
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Interstitial Matrix Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix	Nucleus
	Molecular Function	Protease Binding Protein Binding Peptidase Activity	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Epithelial Cell Development Proteolysis Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process	Regulation Of Transcription, DNA-templated
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Generic Transcription Pathway
Drugs
Diseases		Ectopia lentis
GWAS		Coronary artery disease ( 29212778) Migraine ( 27322543) Rhegmatogenous retinal detachment ( 23585552)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		110 interacting genes: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 CATSPER1 CCDC26 CFAP206 CHCHD2 CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL2 GNE GNMT GOLGA8EP HGF HNRNPLL HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LHX4 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 OTX1 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SHFL SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	43 interacting genes: ADAMTSL4 CARD9 CCDC136 CEP44 CEP70 CSRNP1 FSD2 GOLGA2 GOPC HMBOX1 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP5-9 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PLSCR1 PNMA2 PRPF31 RUNDC3A SMAD9 SPRY2 SSX2IP STX11 TCF4 TMCC2 TNS2 TRAF1 TRIM36 TRIM41 TRIM54 TSGA10 ZBTB8A ZNF417
Entrez ID		54507	84914
HPRD ID		18237	15864
Ensembl ID		ENSG00000143382	ENSG00000198466
Uniprot IDs		B7ZMJ3 Q6UY14 Q9UFG7	Q96SQ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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