PCBP2 and SRSF7

Number of citations of the paper that reports this interaction (PubMedID 8871564)
22

Data Source:
HPRD (two hybrid, in vivo)

		PCBP2	SRSF7
Description		poly(rC) binding protein 2	serine and arginine rich splicing factor 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding C-rich Single-stranded DNA Binding	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus IRES-dependent Viral Translational Initiation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		27 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3	14 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 NEDD4 NXF1 PCBP2 SDCBP SREK1 SRPK1 SRPK2
Entrez ID		5094	6432
HPRD ID		03129	08991
Ensembl ID		ENSG00000197111	ENSG00000115875
Uniprot IDs		A0A384N6B9 Q15366	Q16629
PDB IDs		2AXY 2JZX 2P2R 2PQU 2PY9	2HVZ
Enriched GO Terms of Interacting Partners?
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