PCBP2 and WDR77

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		PCBP2	WDR77
Description		poly(rC) binding protein 2	WD repeat domain 77
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding C-rich Single-stranded DNA Binding	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus IRES-dependent Viral Translational Initiation	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling	snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		27 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3	44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		5094	79084
HPRD ID		03129	14387
Ensembl ID		ENSG00000197111	ENSG00000116455
Uniprot IDs		A0A384N6B9 Q15366	A0A024R0H7 Q9BQA1
PDB IDs		2AXY 2JZX 2P2R 2PQU 2PY9	4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S
Enriched GO Terms of Interacting Partners?
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