CHMP4A and TTC19

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP4A	TTC19
Description		charged multivesicular body protein 4A	tetratricopeptide repeat domain 19
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Cell Nucleus Cytoplasm Endosome Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Membrane Invagination Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		12 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A	12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B
Entrez ID		29082	54902
HPRD ID		16597	07899
Ensembl ID		ENSG00000254505	ENSG00000011295
Uniprot IDs		Q9BY43	A0A024RD83 Q6DKK2
PDB IDs		3C3O 5MK1
Enriched GO Terms of Interacting Partners?
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