CHMP4A and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 14505570)
373

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP4A	CHMP4C
Description		charged multivesicular body protein 4A	charged multivesicular body protein 4C
Image
GO Annotations	Cellular Component	ESCRT III Complex Cell Nucleus Cytoplasm Endosome Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane	ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Membrane Invagination Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS			Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		12 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		29082	92421
HPRD ID		16597	18135
Ensembl ID		ENSG00000254505	ENSG00000164695
Uniprot IDs		Q9BY43	Q96CF2
PDB IDs		3C3O 5MK1	3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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