SETD2 and HTT

  • Number of citations of the paper that reports this interaction (PubMedID 9700202)
  • 116
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

SETD2

HTT

Description SET domain containing 2, histone lysine methyltransferase huntingtin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • HDL cholesterol ( 24097068 30275531)
  • HDL cholesterol levels ( 28334899)
  • Huntington's disease progression ( 28642124)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 27863252)
  • Platelet distribution width ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • White blood cell count ( 27863252)
  • White blood cell count (basophil) ( 27863252)
  • Alcohol consumption ( 31358974)
  • Estimated glomerular filtration rate ( 31152163)
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Monobrow ( 27182965)
  • Serum sulfate level ( 27412988)
  • Tuberculosis ( 29036319)
  • Type 2 diabetes ( 30297969)
  • Worry too long after an embarrassing experience ( 29500382)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes 8 interacting genes: ATXN1 CIC H3-4 H3C1 HTT SIAH2 SMAD3 SPOP 109 interacting genes: AKT1 AMFR AP2A2 CASP1 CASP3 CASP6 CBS CEP126 CHD3 CHUK CREBBP CRMP1 CTBP1 DLG4 DNALI1 DPPA4 DUSP10 ECH1 EGFR ELP1 ERCC6L ETV4 EVL F8A1 FEZ1 FICD FTL GAPDH GGA2 GIT1 GOLPH3L GPRASP2 GRB2 H2AP H3C10 HAP1 HEYL HIP1 HIP1R HOXC11 HOXC4 HSP90AA1 HSPA8 HYPK IFT20 IKBKB ING5 KAT2B MAGEA3 MAGEB18 MAGEB6 MAP3K10 MBD1 MED21 MED31 MID1 MRFAP1 MRFAP1L1 MTSS1 NCOR1 NUP58 OPTN OSTF1 PACSIN1 PDK2 PEX11B PFN2 PIAS1 PIAS4 PIK3R1 PML PPP2CA PRPF40A PRPF40B PSMC5 RASA1 REST RHEB RNF20 RPS6KB1 SAP30 SETD2 SH3GL3 SH3GLB1 SIN3A SP1 SUMO1 SYMPK TACC1 TAF4 TBP TCERG1 TGM2 TP53 TPR TRAFD1 TRIP10 TTC23 TUBB UBAC1 UBE2E3 UBE2K UTP14A VCP XRCC6 ZDHHC17 ZFYVE19 ZNF451 ZNF655
Entrez ID 29072 3064
HPRD ID 11043 00883
Ensembl ID ENSG00000181555 ENSG00000197386
Uniprot IDs Q9BYW2 P42858
PDB IDs 2A7O 2MDC 2MDI 2MDJ 4FMU 4H12 5JJY 5JLB 5JLE 5LSS 5LSX 5LSY 5LSZ 5LT6 5LT7 5LT8 5V21 5V22 2D3X 2LD0 2LD2 3IO4 3IO6 3IOR 3IOT 3IOU 3IOV 3IOW 3LRH 4FE8 4FEB 4FEC 4FED 4RAV 6EZ8 6N8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?