HTT and PACSIN1

  • Number of citations of the paper that reports this interaction (PubMedID 12354780)
  • 31
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

HTT

PACSIN1

Description huntingtin protein kinase C and casein kinase substrate in neurons 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption ( 31358974)
  • Estimated glomerular filtration rate ( 31152163)
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Monobrow ( 27182965)
  • Serum sulfate level ( 27412988)
  • Tuberculosis ( 29036319)
  • Type 2 diabetes ( 30297969)
  • Worry too long after an embarrassing experience ( 29500382)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body mass index ( 29273807 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Free thyroxine concentration ( 30367059)
  • High density lipoprotein cholesterol levels ( 30498476)
  • Inflammatory bowel disease ( 27569725)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 109 interacting genes: AKT1 AMFR AP2A2 CASP1 CASP3 CASP6 CBS CEP126 CHD3 CHUK CREBBP CRMP1 CTBP1 DLG4 DNALI1 DPPA4 DUSP10 ECH1 EGFR ELP1 ERCC6L ETV4 EVL F8A1 FEZ1 FICD FTL GAPDH GGA2 GIT1 GOLPH3L GPRASP2 GRB2 H2AP H3C10 HAP1 HEYL HIP1 HIP1R HOXC11 HOXC4 HSP90AA1 HSPA8 HYPK IFT20 IKBKB ING5 KAT2B MAGEA3 MAGEB18 MAGEB6 MAP3K10 MBD1 MED21 MED31 MID1 MRFAP1 MRFAP1L1 MTSS1 NCOR1 NUP58 OPTN OSTF1 PACSIN1 PDK2 PEX11B PFN2 PIAS1 PIAS4 PIK3R1 PML PPP2CA PRPF40A PRPF40B PSMC5 RASA1 REST RHEB RNF20 RPS6KB1 SAP30 SETD2 SH3GL3 SH3GLB1 SIN3A SP1 SUMO1 SYMPK TACC1 TAF4 TBP TCERG1 TGM2 TP53 TPR TRAFD1 TRIP10 TTC23 TUBB UBAC1 UBE2E3 UBE2K UTP14A VCP XRCC6 ZDHHC17 ZFYVE19 ZNF451 ZNF655 24 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID 3064 29993
HPRD ID 00883 05936
Ensembl ID ENSG00000197386 ENSG00000124507
Uniprot IDs P42858 Q5TZC3 Q9BY11
PDB IDs 2D3X 2LD0 2LD2 3IO4 3IO6 3IOR 3IOT 3IOU 3IOV 3IOW 3LRH 4FE8 4FEB 4FEC 4FED 4RAV 6EZ8 6N8C 3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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