SETD2 and SIAH2

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

SETD2

SIAH2

Description SET domain containing 2, histone lysine methyltransferase siah E3 ubiquitin protein ligase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • HDL cholesterol ( 24097068 30275531)
  • HDL cholesterol levels ( 28334899)
  • Huntington's disease progression ( 28642124)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 27863252)
  • Platelet distribution width ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • White blood cell count ( 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 8 interacting genes: ATXN1 CIC H3-4 H3C1 HTT SIAH2 SMAD3 SPOP 43 interacting genes: AFF1 AKR1C3 ATN1 CACYBP CCBE1 CHEK2 DCC DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 NRF1 OPRM1 PEG10 PEG3 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 UBE2N UBE2V2 USP13 USP19 VAV1
Entrez ID 29072 6478
HPRD ID 11043 03737
Ensembl ID ENSG00000181555 ENSG00000181788
Uniprot IDs Q9BYW2 O43255
PDB IDs 2A7O 2MDC 2MDI 2MDJ 4FMU 4H12 5JJY 5JLB 5JLE 5LSS 5LSX 5LSY 5LSZ 5LT6 5LT7 5LT8 5V21 5V22 5H9M
Enriched GO Terms of Interacting Partners?
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