CEP57L1 and EXOC8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CEP57L1	EXOC8
Description		centrosomal protein 57 like 1	exocyst complex component 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Centrosome Microtubule	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding Microtubule Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding Ral GTPase Binding Phosphatidylinositol Binding
	Biological Process	Biological_process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Midgestational circulating levels of PCBs ( 28235828) Prostate cancer ( 23535732)	Hemoglobin concentration ( 27863252)
Interacting Genes		74 interacting genes: AKT1 ALOX5 AP1M1 ARNT2 BRCA1 BYSL CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 CFAP206 DISC1 DYDC1 ELOA EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NEFL NOTCH1 NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 TAB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB VPS28 ZGPAT	21 interacting genes: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA SASH1 TADA2A ULK1 USHBP1
Entrez ID		285753	149371
HPRD ID		10792	09943
Ensembl ID		ENSG00000183137	ENSG00000116903
Uniprot IDs		E5RFY4 G3V140 Q8IYX8	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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