CEP57L1 and TAB3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CEP57L1	TAB3
Description		centrosomal protein 57 like 1	TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Centrosome Microtubule	Cytosol Plasma Membrane Endosome Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Microtubule Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding Metal Ion Binding
	Biological Process	Biological_process	Activation Of MAPK Activity Stimulatory C-type Lectin Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Negative Regulation Of Autophagy Fc-epsilon Receptor Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Interleukin-1-mediated Signaling Pathway
Pathways			NOD1/2 Signaling Pathway FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS		Midgestational circulating levels of PCBs ( 28235828) Prostate cancer ( 23535732)
Interacting Genes		74 interacting genes: AKT1 ALOX5 AP1M1 ARNT2 BRCA1 BYSL CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 CFAP206 DISC1 DYDC1 ELOA EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NEFL NOTCH1 NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 TAB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB VPS28 ZGPAT	9 interacting genes: CEP57L1 IKBKG MAP3K7CL OGT PIN1 PPIL3 TAB1 TRAF2 TRAF6
Entrez ID		285753	257397
HPRD ID		10792	06738
Ensembl ID		ENSG00000183137	ENSG00000157625
Uniprot IDs		E5RFY4 G3V140 Q8IYX8	Q8N5C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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