EXOC8 and BLOC1S6

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		EXOC8	BLOC1S6
Description		exocyst complex component 8	biogenesis of lysosomal organelles complex 1 subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm	Cell Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm
	Molecular Function	Protein Binding Ral GTPase Binding Phosphatidylinositol Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)
Interacting Genes		21 interacting genes: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA SASH1 TADA2A ULK1 USHBP1	38 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WASHC3
Entrez ID		149371	26258
HPRD ID		09943	16055
Ensembl ID		ENSG00000116903	ENSG00000104164
Uniprot IDs		Q8IYI6	B3KY40 H3BST1 Q9UL45
PDB IDs
Enriched GO Terms of Interacting Partners?
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