SALL3 and CRBN

Number of citations of the paper that reports this interaction (PubMedID 30385546)
17

Data Source:
BioGRID (pull down)

		SALL3	CRBN
Description		spalt like transcription factor 3	cereblon
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Metal Ion Binding	Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Olfactory Bulb Interneuron Development Forelimb Morphogenesis Hindlimb Morphogenesis Negative Regulation Of Smoothened Signaling Pathway	Protein Ubiquitination Negative Regulation Of Protein Complex Assembly Positive Regulation Of Protein Complex Assembly Negative Regulation Of Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs			Lenalidomide Thalidomide Pomalidomide
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Attention function in attention deficit hyperactive disorder ( 26174813) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Metabolite levels ( 23823483) Prostate cancer ( 23535732) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Rheumatoid arthritis ( 18668548) Smoking initiation (ever regular vs never regular) ( 31089300) Subcutaneous adipose tissue ( 22589738)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Immune response to smallpox vaccine (IL-6) ( 22542470) Knee osteoarthritis ( 27696742) Restless legs syndrome ( 29029846) White blood cell count (basophil) ( 29403010 27863252) White matter integrity ( 23218918)
Interacting Genes		1 interacting genes: CRBN	33 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A OSR1 OSR2 PAK5 PIK3R3 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91
Entrez ID		27164	51185
HPRD ID		05467	16750
Ensembl ID		ENSG00000256463	ENSG00000113851
Uniprot IDs		A0A384MEH2 A9JR48 Q9BXA9	Q96SW2
PDB IDs			4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G
Enriched GO Terms of Interacting Partners?
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