CYFIP2 and ABI3

Number of citations of the paper that reports this interaction (PubMedID 17101133)
13

Data Source:
HPRD (in vivo)

		CYFIP2	ABI3
Description		cytoplasmic FMR1 interacting protein 2	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Cell Junction SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Membrane Lamellipodium
	Molecular Function	RNA 7-methylguanosine Cap Binding Protein Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	Cell Morphogenesis Apoptotic Process Axon Guidance Cell Projection Assembly Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Dendrite Extension Cell-cell Adhesion	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010) Lung function (FEV1/FVC) ( 28166213 30804560) Peak expiratory flow ( 30804560)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)
Interacting Genes		22 interacting genes: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP F2RL1 FMR1 FXR1 FXR2 GAS7 MTDH NCK1 NCKAP1 PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A	36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2
Entrez ID		26999	51225
HPRD ID		07556	05900
Ensembl ID		ENSG00000055163	ENSG00000108798
Uniprot IDs		B7Z8N7 E7EVJ5 Q96F07	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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