ABI3 and EIF3H

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		ABI3	EIF3H
Description		ABI family member 3	eukaryotic translation initiation factor 3 subunit H
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Lamellipodium	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Polysomal Ribosome Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Metallopeptidase Activity
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Proteolysis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)	Asthma ( 29273806) Body mass index ( 25673413) Colorectal cancer ( 26965516 25990418 18372905 30529582 21761138 26151821 29471430 24737748) Colorectal cancer or advanced adenoma ( 30510241) Corneal curvature ( 22969067) Height ( 31562340) Metabolite levels ( 23823483) Morning person ( 30696823) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Right lateral prefrontal cortical growth ( 29682794) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2	9 interacting genes: ABI2 ABI3 CCDC85B DISC1 EIF3G EIF3K NCK2 SORBS3 SPTBN1
Entrez ID		51225	8667
HPRD ID		05900	04885
Ensembl ID		ENSG00000108798	ENSG00000147677
Uniprot IDs		Q9P2A4	O15372 Q6IB98
PDB IDs			3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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