ABI3 and KLC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ABI3	KLC3
Description		ABI family member 3	kinesin light chain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Lamellipodium	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding	Microtubule Motor Activity Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration	Axo-dendritic Transport
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2	37 interacting genes: ABI3 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		51225	147700
HPRD ID		05900	03212
Ensembl ID		ENSG00000108798	ENSG00000104892
Uniprot IDs		Q9P2A4	A0A024R0V3 Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?
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