ABI3 and WASF2

Number of citations of the paper that reports this interaction (PubMedID 17101133)
13

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		ABI3	WASF2
Description		ABI family member 3	WASP family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Lamellipodium	Ruffle Early Endosome Cytosol Cell-cell Junction Actin Cytoskeleton Lamellipodium SCAR Complex Protein-containing Complex Synapse Extracellular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding	Actin Binding Protein Binding SH3 Domain Binding Cadherin Binding Protein Kinase A Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration	Angiogenesis Ameboidal-type Cell Migration Endocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Lamellipodium Assembly Viral Process Rac Protein Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Actin Filament-based Movement Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Stress Fiber Assembly Lamellipodium Morphogenesis Postsynaptic Actin Cytoskeleton Organization
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)	Systolic blood pressure ( 30578418)
Interacting Genes		36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2	23 interacting genes: ABI1 ABI2 ABI3 ABL1 ACTB ACTR2 ACTR3 APBB1 ARPC3 BAIAP2 BTK CDC42 CYFIP2 DOCK1 FYN GAS7 GRB2 ITSN2 NCKAP1 PACSIN1 PRPF40A PSTPIP1 TCERG1
Entrez ID		51225	10163
HPRD ID		05900	05796
Ensembl ID		ENSG00000108798	ENSG00000158195
Uniprot IDs		Q9P2A4	Q9Y6W5
PDB IDs			2A40
Enriched GO Terms of Interacting Partners?
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