APPL1 and DOK3

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 22
  • Data Source:
  • BioGRID (two hybrid)

APPL1

DOK3

Description adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 docking protein 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 29212778)
  • Inflammatory bowel disease ( 23128233)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 45 interacting genes: ADIPOR1 ADIPOR2 AKT1 AKT2 APPL2 BATF3 BRWD1 CBL CBLB CMTM4 DCC DOK2 DOK3 DOK7 DPYSL5 EGFR FARS2 FSHR HDAC2 ID1 IMPDH2 INO80E KLF15 KXD1 MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 PIK3CA PIK3R1 PIK3R2 PLEKHF2 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 TP53 TRAF2 UBE2O ZNF829 20 interacting genes: ABL1 ANKS1A APPL1 APPL2 CRK CSK DOK1 DOK2 DOK5 FYN INPP5D LCK LYN RBPMS RET RIN3 SHE STAT3 TNS2 TRAF1
Entrez ID 26060 79930
HPRD ID 05053 16834
Ensembl ID ENSG00000157500 ENSG00000146094
Uniprot IDs Q9UKG1 A0A024R7M5 D6RAM3 Q7L591
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B
Enriched GO Terms of Interacting Partners?
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