DOK3 and DOK1

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		DOK3	DOK1
Description		docking protein 3	docking protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane	Nucleus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Ras Protein Signal Transduction Neutrophil Degranulation	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Axon Guidance Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Pathways		Neutrophil degranulation	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RET signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Inflammatory bowel disease ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Height ( 31562340)
Interacting Genes		20 interacting genes: ABL1 ANKS1A APPL1 APPL2 CRK CSK DOK1 DOK2 DOK5 FYN INPP5D LCK LYN RBPMS RET RIN3 SHE STAT3 TNS2 TRAF1	42 interacting genes: ABL1 ABL2 BCR CRK CRKL CSDE1 CSK DOK3 ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC TLN1 VAV1 YES1
Entrez ID		79930	1796
HPRD ID		16834	04228
Ensembl ID		ENSG00000146094	ENSG00000115325
Uniprot IDs		A0A024R7M5 D6RAM3 Q7L591	B3KP83 B4DJN1 Q14CB2 Q2TA81 Q99704
PDB IDs			2V76
Enriched GO Terms of Interacting Partners?
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