SS18L1 and PCGF6

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		SS18L1	PCGF6
Description		SS18L1 subunit of BAF chromatin remodeling complex	polycomb group ring finger 6
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleus Nucleoplasm Cytosol Nuclear Body NBAF Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Dendrite Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition
Pathways			Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		31 interacting genes: AATF ANKRD22 ATF3 BRD1 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NR1H3 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC STAT3 TAF9B TCF7	22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21
Entrez ID		26039	84108
HPRD ID		09398	07427
Ensembl ID		ENSG00000184402	ENSG00000156374
Uniprot IDs		B4DSR7 O75177	Q9BYE7
PDB IDs			2DJB
Enriched GO Terms of Interacting Partners?
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