PCGF6 and MAGEA1

Number of citations of the paper that reports this interaction (PubMedID 25590999)
15

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PCGF6	MAGEA1
Description		polycomb group ring finger 6	MAGE family member A1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways		Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21	23 interacting genes: CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		84108	4100
HPRD ID		07427	02059
Ensembl ID		ENSG00000156374	ENSG00000198681
Uniprot IDs		Q9BYE7	P43355
PDB IDs		2DJB	1W72 3BO8
Enriched GO Terms of Interacting Partners?
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