ZZZ3 and EPS8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ZZZ3	EPS8
Description		zinc finger ZZ-type containing 3	epidermal growth factor receptor pathway substrate 8
Image
GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus	Plasma Membrane Brush Border Cell Cortex Postsynaptic Density NMDA Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Stereocilium Tip Ruffle Membrane Extracellular Exosome Glutamatergic Synapse
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Actin Binding Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity Signaling Adaptor Activity Rac GTPase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Rho Protein Signal Transduction Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Regulation Of Rho Protein Signal Transduction Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Height ( 31562340) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Obesity ( 23563607) Type 2 diabetes (age of onset) ( 28060188)	Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913)
Interacting Genes		15 interacting genes: BLZF1 DNAJB11 EPS8 FAM124A GATA1 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513	61 interacting genes: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BORCS6 BYSL C19orf25 C6orf141 C8orf33 CASK CBL CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 ITSN2 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RCAN3 RFXAP RSPH14 RUNX1T1 SCRN3 SERPINA5 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XAGE2 XRCC6 ZZZ3
Entrez ID		26009	2059
HPRD ID		15907	02563
Ensembl ID		ENSG00000036549	ENSG00000151491
Uniprot IDs		Q8IYH5	B4E3T6 Q12929
PDB IDs		2FC7 2YUM 6E83 6E86	2E8M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?