ZZZ3 and TRIM22

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ZZZ3	TRIM22
Description		zinc finger ZZ-type containing 3	tripartite motif containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Protein Kinase Binding Protein Binding, Bridging Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Immune Response Response To Virus Positive Regulation Of Autophagy Viral Process Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		HATs acetylate histones	Interferon gamma signaling
Drugs
Diseases
GWAS		Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Height ( 31562340) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Obesity ( 23563607) Type 2 diabetes (age of onset) ( 28060188)	Coronary artery disease ( 29212778)
Interacting Genes		15 interacting genes: BLZF1 DNAJB11 EPS8 FAM124A GATA1 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513	10 interacting genes: CASK CIC CREB1 LGALS3 LGALS8 MFHAS1 RERE TAF7 USP7 ZZZ3
Entrez ID		26009	10346
HPRD ID		15907	05951
Ensembl ID		ENSG00000036549	ENSG00000132274
Uniprot IDs		Q8IYH5	B4DQS5 Q8IYM9
PDB IDs		2FC7 2YUM 6E83 6E86
Enriched GO Terms of Interacting Partners?
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