MSRB3 and PRDM4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MSRB3	PRDM4
Description		methionine sulfoxide reductase B3	PR/SET domain 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol	Nucleus Cytoplasm Histone Methyltransferase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding Histone Methyltransferase Binding
	Biological Process	Response To Oxidative Stress Protein Repair Oxidation-reduction Process	Transcription By RNA Polymerase II Histone H4-R3 Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Protein repair	p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Birth weight ( 31043758) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Differentiated thyroid cancer ( 28703219) FEV1 ( 30804560) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Height ( 31562340) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 28098162 22504421) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 30804560) Papillary thyroid cancer ( 28703219) Peak expiratory flow ( 30804560) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Subcortical brain region volumes ( 25607358) Subiculum volume ( 30279459) Temperament ( 22832960) Temporal lobe volume ( 31396565) Total hippocampal volume ( 30279459) Type 2 diabetes nephropathy ( 21150874)	Acne (severe) ( 24927181) Sleep duration ( 30846698)
Interacting Genes		6 interacting genes: GOLGA2 LNX2 MAPK8IP2 PRDM4 TCF4 TRIP6	6 interacting genes: CTNNBL1 EIF4E EMX1 MSRB3 SERTAD1 SMAD3
Entrez ID		253827	11108
HPRD ID		14785	10425
Ensembl ID		ENSG00000174099	ENSG00000110851
Uniprot IDs		Q8IXL7	A0A024RBM7 B3KPI0 Q9UKN5
PDB IDs			2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?