FSHR and APPL1

  • Number of citations of the paper that reports this interaction (PubMedID 15070827)
  • 36
  • Data Source:
  • HPRD (in vivo, two hybrid)

FSHR

APPL1

Description follicle stimulating hormone receptor adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065)
  • Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877)
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Chronotype ( 30696823)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Erectile dysfunction and prostate cancer treatment ( 20932654)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lean body mass ( 28552196)
  • Low density lipoprotein cholesterol levels ( 30498476)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Polycystic ovary syndrome ( 22885925 21151128)
  • Radiation response ( 20923822)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes 20 interacting genes: AKT2 APPL1 ARR3 CANX CBX5 CGA FSHB GRK2 GRK4 GRK6 MT-RNR2 RPS27A S100A10 TOP1 TUG1 UBA52 UBB UBC YWHAQ ZBTB16 45 interacting genes: ADIPOR1 ADIPOR2 AKT1 AKT2 APPL2 BATF3 BRWD1 CBL CBLB CMTM4 DCC DOK2 DOK3 DOK7 DPYSL5 EGFR FARS2 FSHR HDAC2 ID1 IMPDH2 INO80E KLF15 KXD1 MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 PIK3CA PIK3R1 PIK3R2 PLEKHF2 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 TP53 TRAF2 UBE2O ZNF829
Entrez ID 2492 26060
HPRD ID 00639 05053
Ensembl ID ENSG00000170820 ENSG00000157500
Uniprot IDs A0A1D5RMN4 P23945 Q9UKG1
PDB IDs 1XUN 1XWD 4AY9 4MQW 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B
Enriched GO Terms of Interacting Partners?
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