CNOT6L and LZTR1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		CNOT6L	LZTR1
Description		CCR4-NOT transcription complex subunit 6 like	leucine zipper like transcription regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol CCR4-NOT Complex	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	3'-5'-exoribonuclease Activity Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity Ras GTPase Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of Cell Proliferation Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing By RNA MRNA Destabilization RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Tuberculosis ( 24057671)
Interacting Genes		3 interacting genes: LZTR1 TNRC6A ZSCAN1	54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		246175	8216
HPRD ID		10841	08992
Ensembl ID		ENSG00000138767	ENSG00000099949
Uniprot IDs		B4E0K8 H0Y9Z5 Q96LI5	A0A384NL67 Q8N653
PDB IDs		3NGN 3NGO 3NGQ 5DV2 5DV4
Enriched GO Terms of Interacting Partners?
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