CBLC and NF2

  • Number of citations of the paper that reports this interaction (PubMedID 28205554)
  • 32
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer)

CBLC

NF2

Description Cbl proto-oncogene C neurofibromin 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 24507774)
  • Weight ( 28552196)
  • Carotid atherosclerosis in HIV infection ( 20009918)
Interacting Genes 53 interacting genes: AKT1 BAP1 BIRC2 CCND2 CDK6 CDKN2B CHFR CKM CRK EGFR EPHA2 ERBB2 FGFR4 FYN GLIS2 GRB2 ITCH LATS2 LYN MAP2K3 MDM4 MYC NACAD NF2 NFIC NSD3 OTUD6A OXA1L RAF1 SH3GL3 SHC1 SPRY2 SRC STK11 TERT TGFB1I1 TP53 TRAF4 TRIM46 TRIP6 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2I UBE2K UBE2L3 UBE2L6 UBE2R2 USP2 USP21 ZAP70 66 interacting genes: AGAP2 AKT1 ARAF ARNT AURKA BECN1 CBLC CCNB1IP1 CCND2 CCNE1 CD44 CDK4 CDK6 CDKN2B CDKN2C CTNNB1 DACH1 DCAF1 EGFR EPHA2 ERBB2 EZR FGFR4 FZR1 GLIS2 GRM1 HGF HGS HIF1A IGF1R ITGB1 KAT2A KDELR2 KDM1A LATS1 LATS2 MAP2K3 MAP2K5 MAP3K5 MAPK14 MDM4 MED28 MET MYC PAK1 PDGFRA PRKCA PXN PYGO2 RAF1 RALGDS RASSF1 SCHIP1 SDCBP SGSM3 SLC9A3R1 SOX3 SOX4 SPTBN1 STK11 TARBP2 TERT TP53 TSC1 TTYH2 XPO1
Entrez ID 23624 4771
HPRD ID 09765 06980
Ensembl ID ENSG00000142273 ENSG00000186575
Uniprot IDs Q9ULV8 A0A024R1D9 A0A024R1F6 A0A024R1I0 A0A024R1J8 A0A024R1J9 P35240
PDB IDs 3OP0 3VRN 3VRO 3VRP 3VRQ 3VRR 1H4R 3U8Z 4ZRI 4ZRJ 6CDS
Enriched GO Terms of Interacting Partners?
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