CBLC and SPRY2

  • Number of citations of the paper that reports this interaction (PubMedID 12234920)
  • 72
  • Data Source:
  • HPRD (in vivo, in vitro)

CBLC

SPRY2

Description Cbl proto-oncogene C sprouty RTK signaling antagonist 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 24507774)
  • Weight ( 28552196)
Interacting Genes 53 interacting genes: AKT1 BAP1 BIRC2 CCND2 CDK6 CDKN2B CHFR CKM CRK EGFR EPHA2 ERBB2 FGFR4 FYN GLIS2 GRB2 ITCH LATS2 LYN MAP2K3 MDM4 MYC NACAD NF2 NFIC NSD3 OTUD6A OXA1L RAF1 SH3GL3 SHC1 SPRY2 SRC STK11 TERT TGFB1I1 TP53 TRAF4 TRIM46 TRIP6 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2I UBE2K UBE2L3 UBE2L6 UBE2R2 USP2 USP21 ZAP70 100 interacting genes: ADAMTSL4 AQP1 ATRIP BRAF CATSPER1 CBL CBLB CBLC CHRD CHRNG CREB5 CRIP2 CRMP1 CSTB CTSB DGCR6 DNM2 EIF4E2 FAIM FAM219A FBN1 FBXO7 FRS3 GNE GP9 GPRIN2 GRAP2 GRB2 GRN HEXIM2 HNRNPLL HSD3B7 ITSN1 KDM1A KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LASP1 LCE1B LCE2D LCE3C LCE3E LCE4A LONRF1 MAPKBP1 MDFI MEOX2 MID2 MKNK1 MLLT6 NCK2 NDFIP2 NEDD4 NR1H2 NUBP1 OTX1 PACSIN3 PLSCR1 PRKAB2 PRKCD PRKD1 PTGER3 PTPN11 RAF1 RTF2 RUNX1T1 SDHB SEMA5B SH3KBP1 SHFL SIAH2 SPRY1 STK16 TCAF1 TMEM14B TNS2 TRAF2 TRIM51 TXNDC5 UBASH3A UBASH3B UBR1 USP20 VPS25 VPS36 ZBTB16 ZNF266 ZNF417 ZNF587
Entrez ID 23624 10253
HPRD ID 09765 03916
Ensembl ID ENSG00000142273 ENSG00000136158
Uniprot IDs Q9ULV8 O43597
PDB IDs 3OP0 3VRN 3VRO 3VRP 3VRQ 3VRR 3BUM 3OB1 5HKY 5HKZ 5HL0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?