FAM168A and SF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM168A	SF1
Description		family with sequence similarity 168 member A	splicing factor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body
	Molecular Function	Protein Binding	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding
	Biological Process	Positive Regulation Of Base-excision Repair	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS		Blood protein levels ( 28240269) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30061609) Pulmonary function (smoking interaction) ( 23284291) Waist-hip ratio ( 28552196)	Urate levels ( 21768215)
Interacting Genes		24 interacting genes: C1orf94 CALCOCO2 DAB1 DAZAP2 DTX2 FBXW5 HGS KLHL42 NAF1 OTUB2 OTULIN PRR20A R3HDM2 RBFOX1 RBPMS SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TNIP1 UBASH3B UBE2V1 VPS37C	43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		23201	7536
HPRD ID		13792	03306
Ensembl ID		ENSG00000054965	ENSG00000168066
Uniprot IDs		Q92567	A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637
PDB IDs			1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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