FAM168A and KLHL42

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM168A	KLHL42
Description		family with sequence similarity 168 member A	kelch like family member 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Positive Regulation Of Base-excision Repair	Protein Polyubiquitination Cell Cycle Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cell Division
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30061609) Pulmonary function (smoking interaction) ( 23284291) Waist-hip ratio ( 28552196)	Gut microbiota (functional units) ( 27694959) Height ( 31562340) Osteoarthritis (hip) ( 30664745) Resting heart rate ( 27798624) Type 2 diabetes ( 30054458)
Interacting Genes		24 interacting genes: C1orf94 CALCOCO2 DAB1 DAZAP2 DTX2 FBXW5 HGS KLHL42 NAF1 OTUB2 OTULIN PRR20A R3HDM2 RBFOX1 RBPMS SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TNIP1 UBASH3B UBE2V1 VPS37C	15 interacting genes: CALCOCO2 COIL CUL3 DDI1 FAM168A RCN3 SERTAD1 SSX2IP STAM2 STXBP4 TRIM23 UBE2E3 UBQLN1 UBQLN4 USHBP1
Entrez ID		23201	57542
HPRD ID		13792	17237
Ensembl ID		ENSG00000054965	ENSG00000087448
Uniprot IDs		Q92567	B2RNT7 F5H523 Q9P2K6
PDB IDs
Enriched GO Terms of Interacting Partners?
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