MLXIP and MLX

Number of citations of the paper that reports this interaction (PubMedID 11073985)
46

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		MLXIP	MLX
Description		MLX interacting protein	MAX dimerization protein MLX
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Mitochondrial Outer Membrane	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Dimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Body mass index ( 29273807) Diastolic blood pressure ( 30224653) Serum uric acid levels ( 30993211) Urate levels ( 31578528)	Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)
Interacting Genes		3 interacting genes: CNPY2 MLX YWHAB	14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32
Entrez ID		22877	6945
HPRD ID		10478	04278
Ensembl ID		ENSG00000175727	ENSG00000108788
Uniprot IDs		Q9HAP2	Q9UH92
PDB IDs
Enriched GO Terms of Interacting Partners?
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