MRAS and LZTR1

Number of citations of the paper that reports this interaction (PubMedID 31337872)
1

Data Source:
BioGRID (enzymatic study)

		MRAS	LZTR1
Description		muscle RAS oncogene homolog	leucine zipper like transcription regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	DNA-binding Transcription Factor Activity Ras GTPase Binding
	Biological Process	Ras Protein Signal Transduction Multicellular Organism Development Muscle Organ Development Actin Cytoskeleton Organization Cellular Response To Leukemia Inhibitory Factor	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blond vs. brown/black hair color ( 30531825) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Chronotype ( 30696823) Coronary artery disease ( 29212778 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 19198612 21378990) Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		12 interacting genes: AFDN BRAF ELOC LZTR1 PIK3CA RAF1 RALGDS RAPGEF5 RAPGEF6 RASIP1 RASSF5 RHOU	54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		22808	8216
HPRD ID		06662	08992
Ensembl ID		ENSG00000158186	ENSG00000099949
Uniprot IDs		O14807 Q6FGP0 Q8WVM9	A0A384NL67 Q8N653
PDB IDs
Enriched GO Terms of Interacting Partners?
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