FCAR and CD79A

Number of citations of the paper that reports this interaction (PubMedID 10438530)
30

Data Source:
HPRD (in vivo)

		FCAR	CD79A
Description		Fc fragment of IgA receptor	CD79a molecule
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	IgA Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Immune Response Neutrophil Degranulation	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways		Neutrophil degranulation	CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Blood protein levels ( 28240269) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: CD79A FCGR1A LYN OSCAR PILRA PPP2CA	17 interacting genes: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM JCHAIN LCK LYN PIGR PTPN6 SYK
Entrez ID		2204	973
HPRD ID		00914	00203
Ensembl ID		ENSG00000186431	ENSG00000105369
Uniprot IDs		A0A024R4N4 A0A024R4R4 P24071	P11912
PDB IDs		1OVZ 1OW0 1UCT	1CV9
Enriched GO Terms of Interacting Partners?
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