ATN1 and KAT7

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	KAT7
Description		atrophin 1	lysine acetyltransferase 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	DNA Replication Origin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process	DNA Replication Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Stress-activated Protein Kinase Signaling Cascade Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus
Pathways		Regulation of PTEN gene transcription	HATs acetylate histones
Drugs
Diseases		Dentatorubropallidoluysian atrophy (DRPLA)
GWAS			Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252)
Interacting Genes		93 interacting genes: AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPOP STXBP4 SYVN1 TEP1 TLE1 TLE5 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	43 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		1822	11143
HPRD ID		06311	07135
Ensembl ID		ENSG00000111676	ENSG00000136504
Uniprot IDs		P54259 Q86V38	O95251
PDB IDs			5GK9
Enriched GO Terms of Interacting Partners?
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