ATN1 and RNF115

Number of citations of the paper that reports this interaction (PubMedID 22315970)
11

Data Source:
BioGRID (two hybrid)

		ATN1	RNF115
Description		atrophin 1	ring finger protein 115
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process	Protein Polyubiquitination Protein Ubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination
Pathways		Regulation of PTEN gene transcription	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Dentatorubropallidoluysian atrophy (DRPLA)
GWAS			Breast cancer ( 25751625 29059683)
Interacting Genes		93 interacting genes: AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPOP STXBP4 SYVN1 TEP1 TLE1 TLE5 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	31 interacting genes: AKT1 APP ATN1 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2
Entrez ID		1822	27246
HPRD ID		06311	18328
Ensembl ID		ENSG00000111676	ENSG00000265491
Uniprot IDs		P54259 Q86V38	Q9Y4L5
PDB IDs
Enriched GO Terms of Interacting Partners?
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