DGKH and TRAF5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		DGKH	TRAF5
Description		diacylglycerol kinase eta	TNF receptor associated factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Plasma Membrane	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Receptor Complex
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation	Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination
Pathways		Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		Bipolar disorder ( 17486107) Blood urea nitrogen levels ( 29403010) Calcium levels ( 24068962) Cortisol levels (saliva) ( 28843169) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate ( 29403010) Height ( 20189936) Kidney stones ( 31729369) Metabolite levels (X-11787) ( 23934736) Nephrolithiasis ( 22396660) Plasma anti-thyroglobulin levels ( 29678681) Pulmonary function in asthmatics ( 25221879) Systolic blood pressure ( 30224653) Urolithiasis ( 30975718)	Household income (MTAG) ( 31844048)
Interacting Genes		2 interacting genes: DGKD TRAF5	45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6
Entrez ID		160851	7188
HPRD ID		07237	03834
Ensembl ID		ENSG00000102780	ENSG00000082512
Uniprot IDs		A8K0I1 B4DYW1 Q86XP1	O00463
PDB IDs
Enriched GO Terms of Interacting Partners?
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