CRX and STK16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CRX	STK16
Description		cone-rod homeobox	serine/threonine kinase 16
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Cytoplasm Golgi-associated Vesicle Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus	Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Interacting Genes		54 interacting genes: ABI2 ACBD4 ATG12 ATM ATXN7 BANF1 BANP C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 DELE1 EIF5A EP300 GCM2 GUCD1 HGS IPO13 KAT2A KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PDC PICALM PID1 PPP1R16B PRKAB2 PRKN PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS ROR2 SFI1 SMAD3 SMUG1 SOX5 STK16 SZT2 TLE5 UBXN2B ZNF688	47 interacting genes: ADAMTSL4 CALCOCO2 CCDC33 CRX CSNK2B DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 IKZF3 INCA1 KCTD14 KCTD17 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP26-1 MBP MEOX2 MGAT5B MIIP MTUS2 NAGK NIF3L1 NOTCH2NLA PCSK5 PLSCR1 PLSCR3 REL RFX6 RPIA SAXO1 SKIL SPRY2 TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6
Entrez ID		1406	8576
HPRD ID		03748	05281
Ensembl ID		ENSG00000105392	ENSG00000115661
Uniprot IDs		O43186	B4DPS1 B8ZZI5 O75716
PDB IDs			2BUJ
Enriched GO Terms of Interacting Partners?
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