CRX and PID1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CRX	PID1
Description		cone-rod homeobox	phosphotyrosine interaction domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus	Negative Regulation Of Protein Phosphorylation Energy Reserve Metabolic Process Positive Regulation Of Gene Expression Regulation Of Mitochondrial Fusion Cellular Response To Leptin Stimulus Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Fat Cell Proliferation Mitochondrion Morphogenesis Cellular Response To Cytokine Stimulus Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To Fatty Acid Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of ATP Biosynthetic Process Positive Regulation Of ATP Biosynthetic Process
Pathways
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS			Chronic obstructive pulmonary disease ( 28166215 30804561) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (antimigraine preparations) ( 31015401) Peak expiratory flow ( 30804560) Pulmonary function (smoking interaction) ( 23284291) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Total cholesterol levels ( 30498476) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		54 interacting genes: ABI2 ACBD4 ATG12 ATM ATXN7 BANF1 BANP C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 DELE1 EIF5A EP300 GCM2 GUCD1 HGS IPO13 KAT2A KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PDC PICALM PID1 PPP1R16B PRKAB2 PRKN PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS ROR2 SFI1 SMAD3 SMUG1 SOX5 STK16 SZT2 TLE5 UBXN2B ZNF688	13 interacting genes: ADAMTSL4 BANP CBY2 CCDC33 CRX GOLGA2 GOPC KRTAP10-1 LRP1 MDFI NME1 NOTCH2NLA THAP1
Entrez ID		1406	55022
HPRD ID		03748	07944
Ensembl ID		ENSG00000105392	ENSG00000153823
Uniprot IDs		O43186	Q7Z2X4
PDB IDs
Enriched GO Terms of Interacting Partners?
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