ABRA and ACTC1

Number of citations of the paper that reports this interaction (PubMedID 11983702)
39

Data Source:
HPRD (in vivo)

		ABRA	ACTC1
Description		actin binding Rho activating protein	actin alpha cardiac muscle 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Sarcomere	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse
	Molecular Function	Actin Binding	ATP Binding ATPase Activity Myosin Binding
	Biological Process	Protein Import Into Nucleus Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration
Pathways			Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Dental caries ( 23259602) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Intraocular pressure ( 31959993 30054594) Metabolite levels ( 23823483)	Axial length ( 24144296) Refractive error ( 20835239)
Interacting Genes		4 interacting genes: ABLIM2 ACTA1 ACTB ACTC1	39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1
Entrez ID		137735	70
HPRD ID		11608	00015
Ensembl ID		ENSG00000174429	ENSG00000159251
Uniprot IDs		Q8N0Z2	B3KPP5 P68032
PDB IDs
Enriched GO Terms of Interacting Partners?
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