KRT40 and SMARCE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRT40	SMARCE1
Description		keratin 40	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding
	Biological Process	Keratinization Cornification	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Keratinization Formation of the cornified envelope	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)
Interacting Genes		322 interacting genes: ADAMTSL3 AEN AKAP17A ALDH3B1 ANKRD36BP1 AP1M1 AQP1 AQP5 ARID5A ARMC7 ARSI ASMTL ATPAF2 AVPI1 AXIN1 BAHD1 BARD1 BCAS2 BEX2 BMS1P1 BYSL C10orf62 C11orf87 C19orf57 C19orf73 C1orf109 C1orf216 C22orf46 C2CD6 C5orf60 C6orf226 C8orf48 CA6 CARD9 CATIP CBX8 CCDC112 CCDC120 CCDC146 CCDC185 CCDC198 CCDC26 CCDC93 CCER1 CCHCR1 CCNG1 CD33 CDC20B CDK18 CDK5R1 CELA2B CEP57 CEP57L1 CFAP206 CHCHD2 CHCHD3 CHIC2 CLEC18A CNTF COL8A1 COMT COX5A CREB5 CTSZ CWF19L2 CYCS CYTH4 DAAM2 DCDC2B DCX DDX6 DLGAP2 DMRT3 DOCK2 DOCK8 DTNB EIF4E2 ELOA EXOC3-AS1 FAM107A FAM124B FAM214A FAM27E3 FAM71C FAM74A4 FAM90A1 FARS2 FASLG FBF1 FBXL18 FBXO34 FBXW5 FKBP1B FNDC11 FOXB1 FRG1 GAD1 GATA2 GATAD2A GEM GFOD1 GGN GLIDR GNAI2 GNG5 GOLGA6L2 GPATCH2L GTF3C5 GUCD1 HAUS1 HBA2 HBZ HCK HDAC4 HGS HNRNPLL HOXA1 HSPA12B HSPD1 ING5 INPP5D IQUB ISCU ITGB5 JOSD1 KAT5 KCTD9 KIFC3 KLHL38 KPNA2 KRT2 KRT20 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LAGE3 LCE3E LENG1 LHX4 LIMS2 LIN37 LINC00636 LINC01588 LMF2 LMO1 LMO2 LMO4 LRCH4 MAB21L2 MAGOHB MAPKBP1 MARK4 MED8 METTL17 MFAP1 MOB3C MOBP MOS MRPL11 MTA1 MXI1 NAB2 NAPRT NDEL1 NEK6 NFKBID NINJ1 NOL4L-DT NPBWR2 NPPB NR1D2 NXF1 OPCML OTUB2 PDLIM5 PGLS PHF21A PIGS PIMREG PIN1 PKD2 POLDIP3 POLL POM121L8P POP5 PPP1R18 PRAM1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMC5 PTGER3 PTPMT1 PXMP2 QPRT RAB3IL1 RAB3IP RAC1 RASSF5 RBM41 RCOR3 RECK RNF213 RNF6 RPL11 RSPH14 RTP5 RWDD2B RXRB SCOC SEMA4C SETD5 SH2D4A SHC3 SHFL SIRPA SLC25A10 SLIRP SLU7 SMARCE1 SMCO4 SNAI1 SNHG11 SNRPB SNW1 SPATA24 SPEF1 SPG7 SRSF2 SSX2 SSX2IP SYT6 TAPBPL TBC1D16 TBC1D22B TCEA2 TCHP TEAD4 THAP7 TIE1 TLE5 TMEM231 TMEM241 TMSB4X TNIP3 TNNT1 TRAF4 TRIM42 TROAP TRPV6 TSC22D4 TSGA10IP TSHZ3 TTC23 TTC25 TTLL10 TXLNA TXN2 TXNDC5 TYK2 TYRO3 UACA UBASH3A UCMA USHBP1 USP2 USP21 UTP14C UTP23 UXT WDR25 WT1 WT1-AS ZBTB16 ZBTB24 ZBTB38 ZC2HC1C ZFHX3 ZFP2 ZFP69B ZFYVE21 ZFYVE26 ZGPAT ZMAT2 ZNF101 ZNF124 ZNF138 ZNF165 ZNF20 ZNF202 ZNF230 ZNF250 ZNF26 ZNF266 ZNF286A ZNF317 ZNF329 ZNF337 ZNF417 ZNF439 ZNF446 ZNF488 ZNF490 ZNF564 ZNF569 ZNF581 ZNF587 ZNF625 ZNF655 ZNF688 ZNF697 ZNF702P ZNF792 ZNF844 ZNRF2P1 ZSCAN21	64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1
Entrez ID		125115	6605
HPRD ID		08304	04382
Ensembl ID		ENSG00000204889	ENSG00000073584
Uniprot IDs		Q6A162	A0A024R1S7 Q969G3
PDB IDs
Enriched GO Terms of Interacting Partners?
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