MID2 and ADAMTSL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MID2	ADAMTSL4
Description		midline 2	ADAMTS like 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Extracellular Exosome	Interstitial Matrix Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix
	Molecular Function	Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Protein Homodimerization Activity Phosphoprotein Binding	Protease Binding Protein Binding Peptidase Activity
	Biological Process	Positive Regulation Of Autophagy Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell	Epithelial Cell Development Proteolysis Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process
Pathways			Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases			Ectopia lentis
GWAS			Coronary artery disease ( 29212778) Migraine ( 27322543) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		118 interacting genes: ADAMTSL4 AEN AQP1 ATRIP AXIN1 BCL6B BRCA1 BRMS1L BYSL CALCOCO2 CBX8 CCDC120 CCDC42 CCHCR1 CEP57L1 CHD2 COX5B CTSZ DCX DGCR6 DGCR6L DMRT3 DYDC1 ELOA FAM107A FAM161A FAM214A FAM90A1 FARS2 FBF1 FBXL18 FRMD6 GFI1B GMCL1 GOLGA2 GORASP2 HNRNPLL HOXB9 IGBP1 IQCN ISCU JOSD1 KIF1A KIFC3 LENG1 LGALS14 LGALS8 MAGOHB METTL17 MFAP1 MID1 MID1IP1 MOS MVP NR1D2 NXF1 OTUB2 PPP1R18 PRPF3 PRPF31 PSMA1 PTCD2 RCOR3 RNF6 RPH3AL RPP25L RUNX1T1 RXRB SCNM1 SDCBP SHFL SLC25A48 SLC25A6 SNAI1 SNAP47 SPAG5 SPATA24 SPG21 SPRY2 STX11 TCAF1 TCEA2 THAP7 TMEM14B TOP3B TRIM27 TRIM29 TRIM32 TRIM42 TRIM54 TRPV6 TSGA10 UBE2D1 UBE2D4 UBE2E2 UBE2E3 UBE2U UBTD1 UNC45A UTP23 UTP25 WT1-AS ZBTB24 ZC2HC1C ZFYVE21 ZGPAT ZNF165 ZNF24 ZNF250 ZNF417 ZNF440 ZNF564 ZNF587 ZNF688 ZNF774 ZNF785 ZNF792 ZSCAN12	110 interacting genes: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 CATSPER1 CCDC26 CFAP206 CHCHD2 CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL2 GNE GNMT GOLGA8EP HGF HNRNPLL HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LHX4 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 OTX1 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SHFL SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		11043	54507
HPRD ID		02191	18237
Ensembl ID		ENSG00000080561	ENSG00000143382
Uniprot IDs		Q6GX22 Q9UJV3	B7ZMJ3 Q6UY14 Q9UFG7
PDB IDs		2DJA 2DMK
Enriched GO Terms of Interacting Partners?
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